A serious error has occurred while trying to send mail into the Exchange Information Store. The Internet Mail Service is being shut down.
Event Information
According to Microsoft: CAUSE: This problem may occur because Exchange Server may be in a low-memory condition. This situation may be experienced when almost no virtual address space is available for virtual memory. RESOLUTION: To resolve this problem, use the following methods in the order in which they are presented. Test to check whether the problem is resolved after you complete each method. If the problem continues to occur, go to the next method. Method 1: Apply the /3GB switch. Method 2: Apply the information store hotfix.